Complete the immunology lab to the best of your ability. No plagiarism. Start with the pre-lab questions and end with the post lab questions after experiment 2.
immunology_lab.docx
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Immunology
PRE-LAB QUESTIONS
1. In the Disease Transmission experiment, you will simulate exposure to a “pathogen.”
Predict whether the rate of exposure (the amount of contacts) will affect an individual’s
chance of becoming infected. Explain your reasoning.
2. Why does an individual with antibodies for a species of Streptococcus bacteria not
automatically have immunity to all bacterial infections?
3. In Experiment 2, you will model and test the effect of the number of antibodies on the
number of pathogens detected. Construct a hypothesis addressing the outcome of the
experiment.
©eScience Labs, 2018
Immunology
EXPERIMENT 1: DISEASE TRANSMISSION
Data Sheet
Table 1: Contact Data
Cup #
Contact 1
Contact 2
Contact 3
Table 2: Test Results per Cup #
Positive (Purple)
Negative (Yellow)
Post-Lab Questions
1. What cup was the original carrier of the disease based on your method? What procedure
did you use to determine this?
2. Look under the cups for the one with the “X”. Does the cup number with the “X” match
the cup you determined from your method? If so, explain why your method worked. If
not, explain what could have been incorrect in your reasoning and how you can modify
your method.
3. What do the cups represent?
©eScience Labs, 2018
Immunology
4. What does the milky solution inside of the cups represent?
5. What does the corn starch represent?
6. Was there a positive and/or negative control in this experiment? If yes, describe them. If
not, describe how a negative and/or positive control could be included.
7. Hypothesize whether the flu would spread faster, slower or at the same rate as food
poisoning. Use the concept of disease transmission to support your hypothesis.
8. What mode of transmission does this experiment best replicate? Explain your answer.
9. In Pre-Lab Question 1, you made a prediction about exposure rate versus chance of
infection. Based on your data, what Cup # had the most contacts throughout the
simulation? Did the cup with the highest number of contacts test positive or negative for
the “disease?” What about the cup with the least number of contacts?
©eScience Labs, 2018
Immunology
EXPERIMENT 2: ANTIBODIES AND THE IMMUNE RESPONSE
Data Sheet
Table 3: Immune Response Model Data
Number of
Antibodies
Mass Trial 1
Mass Trial 2
Mass Trial 3
Average Mass
Post-Lab Questions
1. Create a graph of number of antibodies versus the mass of particles picked up.
Construct your graph on a computer program such as Microsoft Excel®.
2. What do the magnets represent?
3. What do the iron filings represent?
4. What do the sprinkles represent?
5. Draw a conclusion about the number of antibodies versus the number of pathogens
detected.
6. Did the results of the experiment support or refute the hypothesis you constructed in
Pre-Lab Question 3? Use your results to support your answer.
©eScience Labs, 2018
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